One Outs is about baseball and that is not in itself new after all there are many series about baseball especially since the sport is hugely popular in Japan. However, One Outs adds mind games and gambling to it.
Tokuchi Toua, is a gambler pitcher that earns his due by defeating any batter that dares to challenge him. A professional baseball known for his batting prowess looks down on the use of baseball to make 'dirty' money so he challenges Toua. His arrogance means he is taken by surprised by and begins second guessing himself after being unable to bat the ball, in part this is because Toua is able to bring out doubts within people through his pitch control and his ability to gauge exactly how to surprise and confuse his opponents.
Toua, is eventually recruited to this player'S professional baseball team. Toua sees this as a chance to earn money and negotiates a performance based contract based on the numbers of outs he can achieve with the chairmen of the team, whilst any run he gives means he falls into debt.
So, Toua strives to take the team forward to the title just because he wants to make the most money possible whilst at the same time destroying the chairmen that does not care for the team and tries to make the team lose in any way possible. It is an interesting change of pace to normal sports series because it has this mind game and gambling edge and there is a lot of cheating within the sport and its super fun to see Toua against all odds winning.